AB011. Systematic analysis of the genomic landscapes of genitourinary cancers
نویسنده
چکیده
60 vs. 61 to 90 degrees) and randomized to CCh or placebo 2:1 in favour of the former. Post hoc meta-analysis of IMPRESS I and II data revealed that men treated with CCh showed a mean 34% improvement in penile curvature, representing a mean ±SD −17.0±14.8 degree change per subject, compared with a mean 18.2% improvement in placebo treated men, representing a mean −9.3±13.6 degree change per subject (P<0.0001). The mean change in PDQ symptom bother score was significantly improved in treated men vs men on placebo (−2.8±3.8 vs. −1.8±3.5, P=0.0037). Three serious adverse events (corporeal rupture) were surgically repaired. IMPRESS I and II support the clinical efficacy and safety of CCh for the physical and psychological aspects of Peyronie disease.
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